Research & Trials

Page 1 2 3 4 5

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

The ARISE RCT is a multi-centre, randomised, controlled trial of EGDT compared to standard care in patients with severe sepsis presenting to the ED. The study will be conducted in multiple sites ... › More

Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)

Melanoma is a serious and common malignancy in Australia. It is the third most common cancer in Australia and approximately 1000 Australians will die of the disease each year. Neurotropism is an ... › More

Pilot Study to Determine Safety and Efficacy of Orbital Injections of LIPO-102 in Patients With Symptomatic Exophthalmos Associated With Thyroid-related Eye Disease (TED)

This is a pilot study to determine the safety and efficacy of orbital injections of LIPO-102. › More

Audit and Screening Study to Determine the Prevalence of Peripheral Arterial Disease (ACHILLES)

The primary objective of the study is to establish the prevalence of lower extremity peripheral arterial disease (PAD), defined as an ankle-brachial index of less than or equal to 0.9, in subjects ... › More

Safety and Efficacy Study of MPC-4326 for Treatment of Patients With HIV-1 Infection

To evaluate the antiretroviral activity and safety of 200 mg BID and 300 mg BID doses of MPC-4326 administered as monotherapy for 14 days to HIV-1 positive patients. Patients with an initial ... › More

A Study of Ixabepilone as Second Line Therapy for Locally Advanced, Recurrent or Metastatic Endometrial Cancer (IXAMPLE2)

The primary purpose of this study is to investigate whether administration of ixabepilone results in superior outcome as measured by progression free survival (PFS) compared to standard ... › More

TMC435-TiDP16-C205: A Phase II Study of TMC435 in Combination With Pegylated Interferon Alpha-2a and Ribavirin in Patients Infected With Genotype 1 Hepatitis C Virus Who Never Received Treatment

The purpose of this study is to test the efficacy, safety and tolerability of 4 different regimens of TMC435 given in combination with Peginterferon alfa-2a and ribaviron (Standard of Care) as ... › More

Techniques to Improve Efficacy of Second Trimester Medical Termination

Interruption of a pregnancy after 14 weeks gestation may be required when the foetus is dead, severely malformed or in cases of maternal illness. This process is usually conducted medically in ... › More

Repeat Dose Safety Study for Compound to Treat Anaemia

The purpose of this study is to characterise the safety and tolerability of repeat doses of compound 1278863A in healthy subjects. › More

An Open Label Extension Study in Patients With Rheumatoid Arthritis

To evaluate the safety and tolerability of LY2127399 administered as subcutaneous injections for 48 weeks in patients with rheumatoid arthritis. › More

Page 1 2 3 4 5

Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Polycystic Kidney Disease

To demonstrate whether tolvaptan modifies ADPKD progression as measured by changes from baseline (from trial 156-04-251) in total kidney volume (TKV) and renal function. › More

Smoking Termination Opportunity for inPatients (STOP)

The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute › More

Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition (OPTIMA)

The purpose of this study is to use a high-resolution intracoronary imaging modality, called optical coherence tomography (OCT) to examine two different types of coronary artery stents used to treat ... › More

A Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prucalopride (Resolor) Tablets in Subjects With Chronic Constipation

The purpose of this study is to compare the efficacy and safety of prucalopride 2 mg given orally once daily for 12 weeks to those of placebo in treatment of chronic › More