Research & Trials

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Migraine and Healthy Eyes Research Project
Volunteers are invited to participate in a research study assessing the effects of migraine headaches on visual function ... › More

Triggers Related to Recurrent Headaches Research Project 2010
MaTCH- ... › More

Randomized, Double-Blind, Placebo-Controlled Trial Of Pregabalin In Patients With Fibromyalgia.
This study, will compare pregabalin with placebo for the duration of 14 weeks to evaluate the efficacy and safety of pregabalin in patients with fibromyalgia. › More

A Phase III Trial to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
The purpose of this trial is to evaluate the effectiveness (level of pain control) and safety of orally administrated CG5503 Extended Release (ER) (base) at doses of 100-250 mg twice daily in ... › More

Treatment of Insomnia Secondary to Chronic Pain
Several studies have shown that behavioural therapy for chronic pain can be beneficial for chronic pain and that behavioural therapy for insomnia can be beneficial for insomnia. However, seldom do ... › More

Effect of Escitalopram vs Reboxetine on Gastro-Intestinal Sensitivity of Patients With Major Depressive Disorder
Patients with major depressive disorder (MDD) commonly have many gastrointestinal complaints. Gastrointestinal pain is classified into 2 categories: visceral and somatic pain. The main aim of this ... › More

A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or Osteoarthritis
The purpose of this study is to assess the degree of pain control achieved by treatment with fentanyl, administered via adhesive patches applied to the skin ('transdermal system') in patients with ... › More

Randomized, Double-Blind, Placebo-Controlled Trial Of Pregabalin In Patients With Fibromyalgia.
This study, will compare pregabalin with placebo for the duration of 14 weeks to evaluate the efficacy and safety of pregabalin in patients with fibromyalgia. › More

A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee
This project will conduct a randomised clinical trial to evaluate the relative benefits of orthotics as the sole treatment of patellofemoral pain syndrome and also when combined with physiotherapy. ... › More

PROMPT Clinical Trial for Migraine Prevention
Various national and local guidelines demand revision of migraine prevention therapy after 4 to 6 months of treatment. However, there is no evidence from clinical studies to support the validity of ... › More

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A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Patients with Moderate to Severe Active Rheumatoid Arthritis
This randomised, double-blind, parallel group study will compare the efficacy and safety of subcutaneous (sc) versus intravenous (iv) administration of RoActemra/Actemra (tocilizumab) in patients ... › More

A Study in Painful Diabetic Neuropathy (COMBO-DN)
This study will investigate the efficacy of a combination treatment of duloxetine + pregabalin compared with the maximal dose of each drug in monotherapy, in patients with diabetic peripheral › More

Non-Invasive Targeted Electronic Pain Control Device ("Biowave System") Versus Transcutaneous Electrical Nerve Stimulation (TENS) for the Symptomatic Treatment of Chronic Low Back Pain
Low back pain is a common condition, which extols a large cost to society from lost wages.The Biowave System was developed by Biowave Corporation (Biowave), Norwalk, CT. Two wires ... › More

Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain
The purpose of the proposed study is to evaluate the efficacy of the InterX 5000 in relieving chronic neck and shoulder pain. This study will focus on the efficacy of treating patients who have ... › More

The Effects of Reducing Stomach Acid on Post-Tonsillectomy Pain
This study was designed to determine whether post-operative pain following a tonsillectomy can be reduced by adding an antacid-like medication to the medications taken after surgery. It is ... › More

Efficacy Study of Prolotherapy vs Corticosteroid for Tennis Elbow
The purpose of the research is to study the effects of two different injection therapies for the treatment of lateral epicondylitis (tennis elbow). Specifically, we will look at which therapy ... › More

Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain
The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain. › More

Synvisc Injections for Lumbar Facet Joint Pain
The objective of this investigation is to evaluate the safety and efficacy of viscosupplementation in treating symptomatic lumbar facet joint arthropathy. The intended use of the device (Synvisc) is ... › More

PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen Or Naproxen
To answer the question of overall benefit: risk of celecoxib when compared to two most commonly prescribe traditional (non-selective) nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of ... › More

Oral Dexamethasone for Treatment of Migraine
The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the ED [after successful treatment] prevents rebound headache. › More

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