Albumin-bound testosterone refers to testosterone circulating in blood which is bound loosely to the carrier protein albumin. Testosterone binds loosely to albumin, meaning that it can separate in order to bind to other molecules or androgen receptor sites in androgen-regulated cells. Albumin-bound teststerone is considered to be bioavailable, meaning that it is available to body cells, unlike testosterone bound to another carrier protein known as sex hormone binding globulin, which is tightly bound and cannot separate to make itself available to body cells. About half of the testosterone in a person’s blood is albumin-bound.

For more information, see Testosterone.

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