Research & Trials
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)
The ARISE RCT is a multi-centre, randomised, controlled trial of EGDT compared to standard care in patients with severe sepsis presenting to the ED. The study will be conducted in multiple sites ... › More
Lume Lung 2: BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC
The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo (inactive capsule) plus standard pemetrexed therapy in patients ... › More
Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)
The ARTEMIS-IPF study is for people who have been diagnosed with IPF and are between 40 and 80 years of age. People who have been diagnosed early in the disease may be more responsive to ... › More
PulmonarOM (Bacterial Lysates) in Respiratory Tract Infections
Primary aim:To evaluate the efficacy of Pulmonarom in the decrease of interleukin-4/interferon gamma after second period of treatment.Secondary ... › More
Magnetic Resonance Imaging Using Ferumoxytol in Patients With Primary Brain Cancer or Brain Metastases From Lung or Breast Cancer
Rationale: Diagnostic procedures, such as magnetic resonance imaging (MRI) using ferumoxytol, may help find and diagnose primary brain cancer or brain ... › More
Study of Mometasone Furoate Nasal Spray on Sleep Disturbances and Daytime Sleepiness in Subjects With Symptoms Caused by Seasonal Allergies(Study P04608) (COMPLETED)
This study will hope to show that by relieving the patient’s nasal symptoms of seasonal allergies using mometasone furoate nasal spray, the patient will obtain a better quality of night-time ... › More
Asthma Intervention Research 2 (AIR2) Trial
The objective of this randomised, double blind, sham-controlled study is to demonstrate the safety and effectiveness of the Alair System in a population of subjects with severe asthma who are ... › More
Randomised Study of a Simple Weight Loss Program for Obese Patients With Obstructive Sleep Apnoea
The purpose of the study is to determine if weight loss interventions aimed at lifestyle modification (dietary education, food diary pedometer) result in weight loss in patients with mild-moderate ... › More
Intravenous Pertussis Immune Globulin in Patients With Severe Childhood Pertussis Infection
Objective:Assess the efficacy of a single infusion of a high titer pertussis immune globulin for the treatment of severe pertussis in children. › More
Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension
The present trial investigates a possible use of oral bosentan, which is currently approved for the treatment of symptoms of pulmonary arterial hypertension (PAH), to patients suffering from ... › More
A Study of LY2127399 in Patients with Systemic Lupus Erythematosus
The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in patients with active ... › More
A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Patients with Moderate to Severe Active Rheumatoid Arthritis
This randomised, double-blind, parallel group study will compare the efficacy and safety of subcutaneous (sc) versus intravenous (iv) administration of RoActemra/Actemra (tocilizumab) in patients ... › More
Smoking Termination Opportunity for inPatients (STOP)
The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute › More
Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma (DREAM)
The purpose of this study is to show whether mepolizumab given every 4 weeks intravenously (i.v.) can reduce the frequency of asthma exacerbations in ... › More
Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children
The purpose of this study is to determine whether a protein called TREM-1 can be used to differentiate viral and bacterial pneumonias in children who are on ventilator support. We propose that the ... › More
Susceptibility to High Altitude Pulmonary Oedema in Subjects With Increased Hypoxic Pulmonary Vasoconstriction
It has been shown, that subjects susceptible to high altitude pulmonary oedema (HAPE) are characterised by an abnormal increase of pulmonary artery pressure at rest in hypoxia and during exercise in ... › More
Magnetic Resonance Imaging Using Ferumoxytol in Patients With Primary Brain Cancer or Brain Metastases From Lung or Breast Cancer
RATIONALE: Diagnostic procedures, such as magnetic resonance imaging (MRI) using ferumoxytol, may help find and diagnose primary brain cancer or brain metastases.PURPOSE: This randomised ... › More
Omalizumab Use and Asthma-Related Quality of Life in Patients With Severe Persistent Allergic Asthma
This study investigates asthma-related quality of life in Brazilian patients using omalizumab. › More
Identification of Genetic Markers for Cardiopulmonary Diseases (Genotype)
This study is designed to investigate whether an association exists between certain genes/protein levels and the development of various cardiopulmonary diseases. It is hoped that this project will ... › More
The Long Term Effect of Inhaled Hypertonic Saline (6%) in Patients With Non Cystic Fibrosis Bronchiectasis
The purpose of this study is to determine whether the daily inhalation of nebulised hypertonic saline (6%) will decrease the incidence of pulmonary exacerbations and increase the quality of life for ... › More
