Virtual Medical Centre

Drugs

Paracetamol/Codeine

Generic Name: Codeine phosphate; Paracetamol
Product Name: Paracetamol/Codeine

• Indication of Paracetamol/Codeine
• Action of Paracetamol/Codeine
• Dose Advice of Paracetamol/Codeine
• Schedule of Paracetamol/Codeine
• Common side effects of Paracetamol/Codeine
• Uncommon side effects of Paracetamol/Codeine

Indication of Paracetamol/Codeine:

Temporary relief of mild to moderate pain and fever.

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Action of Paracetamol/Codeine:

Panadeine contains two active ingredients- paracetamol and codeine, which work in different ways to reduce pain. Paracetamol has painkilling as well as antipyretic (anti-fever) effects by preventing the production of chemical substances called prostaglandins, which are responsible for the pain and inflammatory response.

Codeine is an opioid analgesic and works by activating opioid receptors in nervous system to produce painkilling effects. It also acts at the level of the spinal cord to prevent the transmission of pain impulses.

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Dose Advice of Paracetamol/Codeine:

Each tablet of Panadeine contains 500 mg paracetamol and 8mg codeine phosphate.

Can be taken with or without food.

Adults: 1-2 tabs 4 hourly; maximum 8 tabs daily.

Children 7-12 years: 1/2-1 tab every 4 hourly; maximum 4 tabs daily.

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