Drugs
Glimel
Generic Name: Glibenclamide
Product Name: Glimel
- Indication of Glimel
- Action of Glimel
- Dose Advice of Glimel
- Schedule of Glimel
- Common side effects of Glimel
- Uncommon side effects of Glimel
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Indication of Glimel:
Glimel is a type of medicine called a sulfonylurea, that lowers blood sugar levels. It is used in the treatment of noninsulin dependent diabetes mellitus (type 2) in addition to dietary management, in those people who cannot control their diabetes by diet alone.Action of Glimel:
Patients with diabetes mellitus have a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar in the blood. Glibenclamide is an antidiabetic medication which is used in those patients with maturity onset or non-insulin dependent diabetes (NIDDM). It works by lowering blood sugar levels by stimulating the production and release of insulin from the pancreas. It also promotes the movement of sugar from the blood into the cells in the body which need it. These two mechanisms, in conjunction with a diet low in sugar and fat, allow diabetics to control their blood sugar levels more effectively.Dose Advice of Glimel:
The dose of glibenclamide is determined by the patient’s blood and urine glucose levels.In newly treated diabetic patients, stabilisation should be commenced with 2.5mg of glibenclamide daily, taken just before breakfast. Blood and urine glucose should be checked after 3-5 days.
If good control has been achieved, the daily dose of 2.5mg is continued as maintenance therapy. If good control has not been achieved, the daily dose should be elevated in steps of 2.5mg at intervals of 7 days, up to a maximum of 15mg or, in exceptional circumstances, 20mg daily.
When patients are transferred form other oral antidiabetic drugs, the recommended starting dose is 2.5 to 5mg/day.
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