Virtual Medical Centre

Drugs

Cefkor CD

Generic Name: Cefaclor monohydrate
Product Name: Cefkor CD

• Indication of Cefkor CD
• Action of Cefkor CD
• Dose Advice of Cefkor CD
• Schedule of Cefkor CD
• Common side effects of Cefkor CD
• Uncommon side effects of Cefkor CD

Indication of Cefkor CD:

Used in the treatment of infectious in adults (and children > 12 years) caused by pathogens susceptible to Cefaclor.
Including: Lower respiratory infections (e.g. community acquired pneumonia, acute bronchitis and exacerbations of chronic bronchitis), Upper respiratory tract infections (e.g. pharyngitis, tonsillitis, acute bacterial sinusitis), lower urinary tract infections, skin and connective tissue structure infections.

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Action of Cefkor CD:

Microbiology.

Cefaclor is a cephalosporin antibiotic with bactericidal activity. It is active against a variety of bacteria responsible for common infections, including some bacteria that are resistant to penicillin and other cephalosporin antibiotics.

Pharmacokinetics.

Cefkor is well absorbed from the gut and peak plasma levels are achieved in close to 2 hours. When taken with food, the time taken to peak plasma levels increases, though the degree of absorption also increases.
Cefaclor is not metabolised.
Plasma half live in healthy patients is about 50 minutes.

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Dose Advice of Cefkor CD:

Adults.
Standard dosage: 375 mg. Twice daily.
Pneumonia, acute bacterial sinusitis: 750 mg, twice daily.

Renal impairment. Administer with caution in patients with severe renal impairment, though dosage adjustments are not usually required.

Use in pregnancy. (Category B1) Safety has not been established. Avoid the use of Cefkor in women of childbearing potential unless its use is considered essential.

Use in lactation. Small amounts of cefaclor are excreted in breast milk. Use with caution in breastfeeding women.

Use in children. Safety and efficacy have not been studied.

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